In my experience, the best-performing heroic melee is a henshin mystic splashed with both rogue and FvS; THF is the most effective form of melee damage at low levels (due to power attack and generic strength amplification, along with cleaves relaying your damage to crowds much more effectively), but synergizing Thief Acrobat in tandem with henshin incorporates much higher attack speed along with colossal base hits. Stick Fighting and Haste Boost allow you to attack frighteningly fast, with almost 50% dodge at heroics. Buff both your strength and charisma - the latter will empower the former, which scales your strength to absolutely scary amounts. This attack speed, with this amount of damage behind every strike, with an Elemental Bloom (level 7 quarterstaff, paralyzing, wisdom drain, extended threat and mult), you'll absolutely shred things.
For the class split itself, I'd either recommend 12 Monk 7 Rogue 1 FvS or 13 Rogue 6 Monk 1 FvS; the former grants more physical damage, and the latter has much more sneak dice. Half-Orc is the best race for either if you have a considerable amount of rAPs, though you'll probably be choosing the races on your RR agenda.
If you want to dex-spec instead of strength, swap FvS with Fighter levels; you can achieve a much larger dodge cap, and incorporate stalwart stance as the demand for defense increases. 10 Rogue 6 Monk 4 Fighter is an extremely good split if you want to travel this route.
In terms of how this compares to shintao monks/THF kensei/barbarians of the same caliber at certain levels - q-staff'ers accumulate much more damage, quicker, in much higher amounts; the defense will likely not exceed a fighter's (though the colossal amount of dodge, or even the PRR bonuses from a fighter-splashed dex-specced q-staff build) will come very close. Barbarians, even at heroics, are still left behind in the very categories they are meant to specialize in. Shintao monks, while absolutely broken at epics, lack the attack speed, utility, and damage (that they accumulate later) to outclass either of these. On top of all of this, you have the saves to evade everything, and the aptitude to disable traps.
TL;DR, roll a q-staff'er. If you don't want to, THF kensei would be the next best in line.
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